Three agencies including the China Center for Disease Control and Prevention announced yesterday (6th) that the “Golden Rice†incident was jointly announced. The GM trial violated relevant regulations, scientific research ethics, and scientific research integrity, and the responsible person was removed from office. The above agencies apologized to the public for the adverse effects caused by the incident. The survey confirmed that in the trial of the Jiangkou Central Elementary School in Hengnan County in 2008, 25 children consumed one meal of “golden riceâ€, which was about 60 grams per person. However, some parents objected to the survey results.
Origin
"Golden rice" test from the storm
In August 2012, the American Journal of Clinical Nutrition published a research paper titled "β-carotene in "Golden Rice" and beta-carotene in oil capsules are equally effective for children's vitamin A supplementation". The main authors are Tang Guangwen of Tufts University, Hu Yuming of the Hunan Provincial Center for Disease Control and Prevention, Yin Shian of the Institute of Nutrition and Food Safety of the Chinese Center for Disease Control and Prevention, and Wang Yin of the Zhejiang Academy of Medical Sciences. The International Environmental Protection Organization’s “Green Peace†immediately condemned the use of GM rice for human trials in children aged 6 to 8 years old in China, setting off an uproar.
Subsequently, the Ministry of Health and the relevant parties in Zhejiang Province and Hunan Province instructed the China Center for Disease Control and Prevention, the Zhejiang Academy of Medical Sciences and the Hunan Provincial Center for Disease Control and Prevention to jointly conduct an in-depth investigation of the issues involved in the paper.
survey
25 children eat 60 grams each
The investigation report of the “Golden Rice†announced yesterday said that the “Golden Rice†test is a “Child Plant Carotene Vitamin A Equivalent Study†project hosted by Tang Guangwen. The project is to study spinach, “golden rice†and beta-carotene. The ability of carotenoids in capsules to be absorbed and converted into vitamin A in children, exploring ways to prevent vitamin A deficiency in children. In 2008, the project was transferred from Zhejiang to Hunan, and was merged with the domestic project “Efficiency of Carotenoids in Plants converted into Vitamin A in Children†carried out by Yonshi An in Hunan, and the primary school in Jiangkou Town, Hengnan County was determined. For the project point.
From May 20 to June 23, 2008, the experiment was carried out at Jiangkou Town Central Primary School. Eighty children were randomly divided into three groups. One group of 25 children consumed 60 grams of “golden rice†per person on lunch on June 2. The "Golden Rice" rice was cooked by Tang Guangwen in the United States and was not reported to the relevant domestic authorities as required, and was brought into China on May 29, 2008. At lunch on June 2, Tang Guangwen and others mixed and heated the “golden rice†rice and white rice and distributed it to the children.
Prior to the trial, the research group had held informed briefings for parents and guardians of students, but did not indicate that the experiment will use genetically modified “golden riceâ€. At the scene, only the last page of the informed consent was signed by the parents and guardians. There was no mention of "golden rice" on this page, not to mention that it was genetically modified rice. The person in charge of the project deliberately used the expression “carbohydrate-rich rice†when signing the informed consent form, deliberately concealing the fact that the “golden rice†was used.
Three responsible persons were disciplined
According to the report, the investigation showed that the “golden rice†used in the project was not approved when it was brought in from abroad and violated the relevant regulations for the safety management of agricultural genetically modified organisms of the State Council; the project deliberately concealed the use of the test in the process of ethical approval and informed consent notification. The genetically modified rice did not provide parents with complete informed consent, violated the provisions of the Ethical Review of Biomedical Research involving People (Trial) and the ethical principles of scientific research, and had academic misconduct; the main parties involved in the project were When accepting the relevant departments to investigate the implementation of the project, concealing facts and providing false information seriously violates the integrity of scientific research.
According to the notification, according to the "Provisional Regulations on Staff Disposition of Institutions", "Measures for Scientific Research Misconduct in Implementation of the National Science and Technology Plan (Trial)" and "Regulations of the Communist Party of China on Disciplinary Disciplinary Regulations", the Chinese Center for Disease Control and Nutrition gave the food to the company. Revocation of the directorship of the maternity and child nutrition office and the reduction of the technical title from the secondary researcher to the third level, so that he cannot conduct scientific research within three years, cancel the qualifications of his doctoral tutor, and the party committee decided to cancel his post within the party; Zhejiang Provincial Health Department Party group Decided to cancel the position of Wang Yin, Director of Science and Technology Department, Zhejiang Provincial Medical Institute. Zhejiang Medical Academy decided to cancel the position of Director of the Nutrition and Food Hygiene Research Office of Wang Yin Health Food Research Institute, cancel its secondary researcher recommendation qualifications, academic qualifications of the Academic Committee and the Institute Qualifications of the members of the Ethics Committee, so that they can not participate in the work of the jury for three years, the party committee of the Zhejiang Medical Academy decided to give its party a warning; the Hunan Provincial Center for Disease Control and Prevention in view of Hu Yuming in the management of the experimental site management, work dereliction of duty Act, decided to withdraw the director of the Hu Yuming Center for Disease Control and Prevention Li, director of the branch office, Hunan CDC party committee decided to give their party warning.
The China Center for Disease Control and Prevention, the Zhejiang Provincial Academy of Medical Sciences and the Hunan Provincial Center for Disease Control and Prevention stated that it will take this as a warning and further strengthen the supervision of scientific research projects, improve internal rules and regulations, strengthen laws and regulations, research integrity, professional ethics and medical ethics education.
question
Contradictions between the list and the number of meals consumed
Both Mr. He and Ms. Qin (a pseudonym) refused to sign compensation agreements and there were objections to the findings. Their children participated in the trial but did not eat "golden rice".
According to a survey jointly announced by the three parties, 80 children were randomly divided into 3 groups. One group of 25 children consumed 60 grams of "Golden Rice" rice for lunch on June 2, 2008, only once. The Hengnan County government reported on November 30 that a total of 88 students participated in the experiment, of which 25 children numbered 36 to 60 had consumed “golden riceâ€.
"After the meeting was held on November 30, people in the county had been doing our ideological work and asked us to sign an agreement and tighten it very hard." Ms. Qin said on the phone yesterday that she could not completely believe the investigation results. " What proof?"
"We did not show us the test records of the time. The list will say 12 boys and 12 girls. Then it will turn into 15 boys and 10 girls. It will change." Ms. Qin also mentioned that the children were in 2008 and In 2009, he took part in related topics. "I have no questions in 2009."
Mr. He believes that in the paper, 24 children were called “golden rice†every day for 21 days. The survey results showed that the number was 25 and they only ate once. The two are obviously contradictory and cannot be convinced.
Jiang Gaoming, a researcher at the Institute of Botany of the Chinese Academy of Sciences, said in a blog last night that although the “Golden Rice†incident has been said, many insiders still do not reveal it. “Does those children who have been tested eat only one GM rice? How about a peer-reviewed academic paper that can be published in an international journal?â€
The compensation plan is irrational
"I didn't sign it and asked them to write a guarantee to ensure that my child grows up healthy, like a girl. It's very simple. But they don't agree, so I don't want this money and I can't buy the happiness of my child's life." Ms. Qin said that although her daughter was very sensible, all kinds of arguments outside her could not have affected her. “I think the children are under great pressure, their tempers are getting bigger, and they suffer great trauma.â€
This is why Mr. He’s son has dropped out of school. “He saw it on the Internet and said that eating this genetically modified food would affect fertility. The biology teacher also mentioned in class that eating 'golden rice' was not good. He felt that his physical development would affect and the resistance would be poor. She refused to go to school in October." The child became very bad tempered and even violent and suicidal. He took his children to Changsha last month, “to find child psychology experts, said that children have psychological and emotional disorders, the degree is very serious.†The child is now taking medication every day.
"Running the hospital does not only cost 10,000 yuan. Why does it cost 80,000 yuan? What about other people? There are no other mental loss fees for other children?" Mr. He thinks that compensation can't be implemented across the board. What he hopes most is that The government can help a psychiatrist to convince the child to go back to school.
Both Mr. He and Ms. Qin have expressed their intention to find a lawyer, but they feel that local lawyers "must not dare to take the case and do not know who to call."
dialogue
Do not want children to live with shadows
Reporter: This matter is solved this way?
Parents (children eating "golden rice" have received compensation money): Almost resolved, with children to the provincial hospital on Sunday, the children are now in school.
Reporter: What are you currently worried about?
Parents: Worries are concerns, but now they are resolved, and they do not want to make trouble again. Everyone has a job, they all have a life, and they calm down earlier. The more worried you are, the worse it will be. It will always come, but we always believe that it will be okay for the little child to eat.
Reporter: Has your child been affected?
Parents: My family is optimistic about this matter, so the children are not affected. If other parents are nervous, children may follow the same attitude.
Reporter: Did the child have any concerns about himself?
Parents: No, I said anything to the children. I said that it was okay, so no matter how the outside children didn't believe it. We do not want to bring this kind of shadow to children, and we do not want children to live with this shadow.
Reporter: Do you believe in the results of the survey?
Parents: I still believe it.
Reporter: I read the report saying that the agreement states that if the child has sequelae, the government will be responsible. Is there any specific way to write the agreement?
Parents: That didn't write.
Reporter: Are you afraid that if something goes wrong, it will not work in the future?
Parents: The government should not.
Reporter: How do you see this experiment and let the children eat the "golden rice" experts?
Parents: I think they should be penalized. But I think everyone has their own interests, so what do you say? It's his interest.
progress
Signing an agreement to receive compensation for family members
The Hengnan County Government informed the parents of the students about the test situation on November 30 in the town of Jiangkou. It also gave a compensation plan: Children who have not eaten “Golden Riceâ€, each family member compensated for the lost work fee of 10,000 yuan; For "Golden Rice" children, each family member compensates 80,000 yuan for lost time and spiritual soothing expenses. The official compensation plan agreement was signed by the parents of 25 children. In order to avoid their concerns, the agreement states that the government will be responsible for any sequelae in the future.
Yesterday afternoon, the parents of some of the students who signed the agreement have received compensation. A parent who asked not to be named told reporters on the phone last night that in the afternoon the county government had sent 80,000 yuan of compensation to the family. According to the agreement, this weekend the children will be arranged to the Provincial City Hospital for inspection.
Expert statement
No "golden rice" found harmful
Xu Haibin, a researcher at the National Food Safety Risk Assessment Center, said that compared with ordinary rice, except for the increase in β-carotene content, there was no change in other nutrients in “golden riceâ€. There is currently no evidence that "golden rice" has adverse effects on human health, and there is no evidence that 60 to 80-year-old children who consume 60 grams of cooked "golden rice" at a time will harm health.
Huang Daxuan, a researcher at the Institute of Biotechnology of the Chinese Academy of Agricultural Sciences, said that in 2009, the United States had conducted a 36-day adult nutrition study on "golden rice". According to officially released scientific data, 200 grams of "golden rice" were taken in one shot per person, and no abnormal health was detected.
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