Controlling and improving the lubrication and cooling conditions of the tool also facilitates the discharge of chips, reduces the friction between the chips and the machined surface or the tool surface, thereby reducing the risk of possible surface quality problems and preventing the resulting The tool is broken or broken. There have been such an example, the machining of the long oil hole of the engine block body, the original use of twist drill, often breaks the drill bit, resulting in the loss of the machine often replaced, and the workpiece will be scrapped. After the drill is changed into a straight groove drill with an inner cooling hole, since the cooling condition is greatly improved, the chips can be smoothly discharged, and the breakage of the drill bit rarely occurs, which improves productivity and reduces tool cost.
Due to the concern about resources and environmental protection and the increasing requirements for operator health protection, how to reduce the consumption of lubricating fluid and reduce the impact on the operator's health caused by the evaporation of lubricating fluid into the air has become an increasingly concerned concern. Focus, people are thinking about and research whether they can use cutting fluid as little as possible or simply do not use cutting fluid. Therefore, a method of cutting with oil mist lubrication has appeared, and dry cutting has been re-emphasized. Some universities, research institutes and enterprises in Germany and the United States have carried out research and experiments in this area. Many enterprises have begun to explore applications in this area. For example, in the processing of long oil holes in engine crankshafts, The traditional practice of cooling and lubricating with coolant during drilling, and the use of spray mist and compressed air to achieve a variety of effects of lubrication, cooling and chip removal. When these new methods are adopted, there will be many new changes in the tribological properties of the cutting tribology system, resulting in new requirements for the tool, and its laws are worthy of further investigation.
According to the theory of cutting tribology, we can better study the influence of tool geometry, tool material on tool life and surface topography of the workpiece, research and develop a new coating suitable for the specific cutting tribology system, or find existing The optimum application conditions of the coating and the applicable cutting parameters enable more effective control of the cutting process.
7. The challenges and rapid development of the tool industry
With the rapid development of China's automobile manufacturing industry, the domestic tool industry is also extremely active and flourishing. Tool companies at home and abroad have taken a fancy to China's big market. The internationally renowned tool and knife accessories companies and their products have almost entered China, such as Sweden's Sadvik with its Coroman, Titex, Walter and other companies, Germany. Mapal, Laitz, Guhring, Israel's Iscar, Japan's OSG, Da Zhaohe, etc., Valinite, Ingosoll, etc. in the United States. When these foreign tool companies first entered China, they were underestimated the development of the Chinese tool market. Some of them only commissioned Chinese agents to sell some of the knives. After-sales service and other work have not been able to keep up, but they gradually realized the market. Importance, began to set up offices in China, and then direct sales in China, the original single agent approach has also begun to change, in the past two years has a new essential change, many foreign tool companies began to set up factories in China, Produce knives and provide various services directly in China. For example, Seco has set up a manufacturing plant in Shanghai, Sandvik has set up a factory in Langfang, Sumitomo Electric has set up a factory in Tianjin, Kenner and Oushi machines have factories in Shanghai, and Lanzhi recently expanded in Nanjing. Its factory has added tool manufacturing and sharpening equipment, and Green's Shanghai-based factory with honing tool manufacturing and grinding functions is about to officially open. The advantages of this approach are obvious. First, it can respond quickly to the market, understand the customer's needs and respond in a timely manner, and shorten the delivery time. Secondly, it can take advantage of China's labor cost, and the tools it produces not only supply Chinese customers. It is also exported to all over the world. The factory in China has become a production base of international famous brand knives with the same quality, same performance and much lower manufacturing cost. The localization of tool manufacturing and services enables suppliers to be closer to end users and better provide on-site support to users. The sales and supply of tools is not only the sale of tools to customers or the delivery of tools to the user site. Tool after-sales service and on-site technical support are sometimes more important. In particular, because the production site sometimes causes abnormal loss of the tool due to various reasons, it can respond to the user's needs in a timely and rapid response, and help the user analyze the cause of the problem and propose a solution. The methods and measures, and try to take some special means to provide the right tool or knife aid in the shortest possible time, to maintain the normal operation of the production line, will directly affect the customer's satisfaction and whether it can establish and maintain long-term Partnerships. At the same time, most tool suppliers have also recognized the importance of helping users reduce tool costs and improve the understanding of tool technology and improve the level of use. Therefore, in the past one or two years, many tool suppliers have been holding various kinds of tools. Technical seminars and training to users, and the development of training centers and tool grinding centers in some important cities in China. For example, Sandvik has set up a large-scale training center called “Efficiency Center†in Shanghai (200 square meters for training workshops and 180 square meters for multiple training classrooms). It is the 19th efficiency center in the world, Titek Sis also set up a grinding center in Shanghai, and Japan's Nagoya Tool Company has long been fascinated by the huge demand for rapid tool manufacturing in China. It has long set up a factory in Shanghai to specialize in manufacturing and grinding various customer needs. The tool is characterized by fast response, regardless of the batch size, and can be directly on-site for direct technical support. In addition, Shubohart has also set up a grinding factory in Shanghai, specializing in the processing and grinding of superhard tools such as diamond tools and CBN tools. Its business volume is also very large, helping many customers solve superhard tools. Grinding work. Arnold has set up factories in Suzhou and Cobalt in Changzhou to provide customers with various tool sharpening work, and to provide on-site services for collecting old tools and sending sharpened tools to the site. At the same time, the professional coating company that coats the tool has also set up a factory in China, on the one hand for the tooling of its original tool manufacturer, and on the other hand for the end user of the tool with the tool coating required. The coating is applied to the finished tool or the tool to be optimized. In this regard, companies such as Balzars and CemeCom have set up factories in Suzhou and other places, and have provided coating services using the most advanced technology. The coated tools provided have been tested and have achieved good results.
At the same time, domestic tool manufacturers and sales companies are also developing rapidly and have made great progress. Zhuzhou Diamond Tool Co., Ltd. has developed into a tool manufacturing enterprise with complete tool manufacturing equipment and a wide range of integrated carbide tools and carbide blades of different specifications to major domestic automobile manufacturers. Zigong Cemented Carbide Co., Ltd. is a large-scale enterprise producing solid carbide and tungsten-molybdenum products in the world. It has a complete production system from tungsten and molybdenum smelting to hard alloy products and tools. It has many years of experience and technical advantages in cemented carbide production. Today's world-class carbide production equipment and processes provide customers with a wide range of indexable inserts and tools for machining such as turning, milling, milling and drilling.
Chengdu Tool Research Institute has been engaged in the research of common technology of precision cutting tools and the production and sales of its high-tech products. The industrialized production base of its scientific research products, various types of cemented carbides, can be indexed by Chengdu Industrial Research Co., Ltd. Tools such as blades have been supplied to domestic and foreign users in batches.
However, the current lack of domestically produced tools is that the quality is not stable enough. Sometimes the batch life is very good, no less than imported tools, but sometimes the life is very low, so it is difficult for the automotive industry to process production control. Since the automobile industry is basically mass-produced, flowing, and has strict requirements on production tempo and productivity, it is generally mandatory to change the tool. If the quality level is unstable, it is difficult to control, or the tool has to be set. The fixed life is shortened, which will increase the cost of the tool and the loss of productivity due to frequent tool changes.
With the increasingly fierce competition in the automotive market, the cost of automobile production must be declining, and accordingly, the cost of tools must also be reduced. One of the methods of reduction is to localize the supply of tools, thereby reducing costs and shortening delivery time. This will provide a good opportunity for many tool companies, and it will also be a huge challenge.
8. Conclusion
The automobile industry is continuing to develop at a high speed. High-quality, high-efficiency, low-cost production has become the basic requirement of market competition. New products, new technologies, new processes, and new materials are constantly appearing. Correspondingly, cutting technology and tools are constantly changing. New requirements were put forward. At present, the surface finish requirement for cutting is higher than before, so the polishing process and the polishing belt and polishing stone used are higher than before, and new quality standards are proposed for the process of deburring, which makes people more In order to pay attention to the surface cleaning and the deburring brush used, it is not the eye-catching tool; the large-scale use of CBN grinding wheel makes the number of times of expensive grinding wheel and its influence on the working life of the grinding wheel become the subject of concern; crankshaft processing The use of vehicles to pull tools and external milling tools needs to be better localized; in order to adapt to the development of high-speed machining, the vibration of the cutting system, the dynamic balance of the tool and the corresponding tool balancing equipment have also become the solution to the processing problems in production. Important considerations; the control of tool grinding technology and tool grinding quality has become a common concern of all automobile manufacturers and tool suppliers; tool new materials and coating technology have always been the research and development hotspots of various tool manufacturers. Automotive manufacturers have the most tools for tool optimization and tool testing. Today, automotive manufacturing has become a simple tool for the supply of tools or tools. It is now required to provide a complete solution for cutting and provide timely and effective on-site technical support. Therefore, in recent years, a new mode of tool management, namely tool outsourcing management, is also being applied and further explored in the automotive industry, giving full play to the role of social division of labor, allowing professional companies with mastery of tool technology and tool management to carry out tools. Purchasing, adjustment, grinding, on-site technical support, problem solving and tool optimization form a partnership with automotive manufacturers to achieve a win-win goal.
For automotive manufacturers and tool manufacturing. For service companies, they face great challenges and will have unprecedented opportunities for development. We believe that both automakers and tool companies will be well positioned to meet this challenge and move to a higher level.
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Bazedoxifene is a selective estrogen receptor modulator (SERM) currently in development for osteoporosis prevention and treatment. IC50 value: Target: estrogen receptor modulator Preclinical and clinical studies with bazedoxifene demonstrate more tissue selectivity than other SERMs. In particular, bazedoxifene has minimal if any agonist activity in the uterus and is able to antagonize effects of estrogen on the uterus. Animal studies and early clinical studies suggest effects in the bone similar to other SERMs with prevention of postmenopausal bone loss
Molecular Weight
470.6
Formula
C₃₀H₃₄N₂O₃
CAS No.
198481-32-2
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere
Bazedoxifene Intermediates,4-Benzyloxy Aniline Hydrochloride In Stock,Bazedoxifene Intermediate Cas 223251-25-0,Cas 51388-20-6 4-Benzyloxy Aniline Hydrochloride
Jinan Meigao Biopharmaceutical Technology Co., Ltd. , http://www.meigaobiopharma.com